volumetry of lateral ventricles in 3-D SPGR MR images using physicians’ knowledge represented by fuzzy logic

S. Kobashi, Y. Hata, E. Matsui(1, H. Kitagaki(2, and E. Mori(3
1)Shimame Medical University,

2)Brain Function Research Institute, Inc.,

3)Hyogo Institute for Aging Brain and Cognitive Disorders,

Proc. 16th International Congress and Exhibition, Computer Assisted Radiology and Surgery (CARS), (2002)

3-D rendering and volumetry of lateral ventricles (LVs) using 3-D SPGR MR images help to diagnose quantitatively and qualitatively many types of cerebral diseases. This paper shows a fully automated method for segmenting lateral ventricles.

Experimental results on 20 normal subjects, 20 Alzheimer’s disease (AD), and 20 normal pressure hydrocephalus

(NPH) showed that their volumetric relation between the cerebrospinal fluid (CSF) and the lateral ventricles were significantly different (P < 0.001). 3-D rendering and volumetric produced by this study can give us a useful tool to assess the brain atrophy.